Current Positions
Role Title: Bioinformatics Scientist - Structural Biology
Contact and submit your resume to: info@cystinebioscience.com
Location: Bethesda, MD.
401K, medical, dental, vision and other benefits along with PTO.
Salary Range : $100K - $150K
Position Overview:
The Bioinformatics Scientist will leverage computational expertise to solve complex biological problems, particularly focusing on protein structure dynamics, immune response analysis, and vaccine design. This role involves developing advanced in silico tools, utilizing machine learning and artificial intelligence techniques, and collaborating across scientific teams to contribute to high-impact research projects.
Key Responsibilities:
Apply molecular dynamics and Monte Carlo simulations to study protein structure dynamics and mechanisms of protein-protein interactions.
Develop and implement in silico tools for designing vaccines and therapeutic products targeting pathogens such as HIV-1, Influenza, and Malaria.
Design and apply methods for analyzing vaccine-elicited immune responses, including the sequence and structural analysis of antibodies.
Create and utilize custom-built AI/ML tools to evaluate vaccine outcomes and related data.
Serve as a subject matter expert to identify biologically significant findings in experimental datasets and collaborate with multidisciplinary teams of scientists.
Utilize High-Performance Computing (HPC) resources to integrate advanced computational techniques, including machine learning, artificial intelligence, and deep learning, into protein and vaccine target design.
Co-lead and coordinate research projects, including but not limited to HIV-1, Malaria, Influenza, and Lassa, collaborating with scientists across organizations and institutions.
Provide scientific expertise to support and advance protein structure and vaccine design efforts.
Mentor interns and postbaccalaureate scientists to foster skill development and scientific growth.
Publish research findings and analysis in peer-reviewed scientific journals
Qualifications:
Ph.D. in Computational Biology, Computational Chemistry, or a related field.
2-3 years of postdoctoral experience in bioinformatics, structural biology, or vaccine-related research.
Strong expertise in molecular dynamics, Monte Carlo simulations, and computational protein analysis.
Experience developing and applying AI/ML tools in biological or biomedical research.
Proficiency in High-Performance Computing (HPC) environments and advanced computational techniques.
Demonstrated ability to collaborate on multidisciplinary projects and mentor junior scientists.
A strong record of publications in peer-reviewed scientific journals.
Comprehensive Benefits Package
Health Coverage:
Choice of 3 Blue Cross Blue Shield (BCBS) health insurance medical plans
Guardian Dental Coverage
Guardian Vision Coverage
Paid Time Off:
Generous paid time off program, including federal holidays
Financial Security:
401(k) retirement plan managed by The Standard
Safe Harbor employer contribution matching
Option for Roth 401(k) contributions
Automatic enrollment for eligible employees (with opt-out option)
Ability to roll over retirement accounts from previous employers
Guardian Life and AD&D (Accidental Death and Dismemberment) Insurance
Health Savings Account with employer match
Additional Perks:
Biweekly paycheck
User-friendly Gusto platform for managing employee information, payroll, and benefits
Online access to 401(k) plan management through The Standard's Personal Savings Center
Employee assistance with retirement planning and investment decisions
Secure online platforms for managing benefits and retirement accounts
Role Title: Biologist
Contact and submit your resume to: info@cystinebioscience.com
Location: Bethesda, MD.
401K, medical, dental, vision and other benefits along with PTO.
Salary Range : $100K - $120K
Position Overview:
The Biologist will play a key role in developing and optimizing assays for vaccine candidates, recombinant proteins, and virus-like particles. This position involves assay development for product characterization, analytical testing, and contributing to the advancement of clinical vaccine candidates. The successful candidate will operate within Good Laboratory Practices (GLP) and Good Manufacturing Practices (GMP) environments.
Key Responsibilities:
Develop and optimize assays for clinical vaccine candidates, including virus vaccines, recombinant proteins, and virus-like particles.
Design and perform cGMP product characterization and release assays, such as:
ELISA (standard, indirect, and Host Cell Protein ELISA), SDS-PAGE, BCA assay, Endotoxin assays, Neutralization assays, and Viral Titer assays.
Operate and troubleshoot laboratory instrumentation, including HPLC (affinity chromatography), PCR, and Flow Cytometry.
Conduct or contribute to projects, either independently or as part of a team, ensuring high-quality scientific output.
Collect, analyze, and interpret experimental data to make meaningful observations and conclusions.
Prepare and present findings at internal meetings and contribute to the preparation of manuscripts and patent applications.
Generate accurate technical reports, protocols, and summaries while maintaining thorough documentation to support GLP/GMP compliance.
Develop and implement new methods, technologies, and processes as needed to advance project objectives.
Apply standard scientific principles and techniques to solve problems and provide solutions across diverse scopes of research.
Required Qualifications:
Bachelor’s degree in Biology or a related scientific discipline.
Minimum of 7 years of experience in vaccine development or related fields, including experience working in GLP and GMP environments.
Strong technical expertise in assay development and analytical testing, with hands-on experience in ELISA, SDS-PAGE, endotoxin assays, and neutralization assays.
Proficiency with laboratory instrumentation, including HPLC, PCR, and Flow Cytometry.
Demonstrated ability to analyze experimental data, troubleshoot assays, and maintain clear and precise documentation.
Comprehensive Benefits Package
Health Coverage:
Choice of 3 Blue Cross Blue Shield (BCBS) health insurance medical plans
Guardian Dental Coverage
Guardian Vision Coverage
Paid Time Off:
Generous paid time off program, including federal holidays
Financial Security:
401(k) retirement plan managed by The Standard
Safe Harbor employer contribution matching
Option for Roth 401(k) contributions
Automatic enrollment for eligible employees (with opt-out option)
Ability to roll over retirement accounts from previous employers
Guardian Life and AD&D (Accidental Death and Dismemberment) Insurance
Health Savings Account with employer match
Additional Perks:
Biweekly paycheck
User-friendly Gusto platform for managing employee information, payroll, and benefits
Online access to 401(k) plan management through The Standard's Personal Savings Center
Employee assistance with retirement planning and investment decisions
Secure online platforms for managing benefits and retirement accounts
